Phytophage

 
Consumer Medicine Information (CMI)

PHYTOPHAGE
 •    Ingredients and active components
Phytophage tablet is made from the standardized dried extract of fenugreek seed with the scientific name Trigonella foenum graceum L.. Fenugreek has tonic, emullient, appetizing, expectorant, antifebrile, galactagogue and hypoglycemic properties.
Each tablet contains at 220 mg of standardized dried extract of fenugreek seed.
Active ingredients: alkaloid, coumarin, tannin, essential oil, protein, saponin, iron, phosphorus.

 
•    What PHYTOPHAGE is used for 

• Adjuvant treatment for type II diabetes

 
•    How PHYTOPHAGE works 
Numerous pharmacological studies and many clinical trials have been carried out regarding the sugar and cholesterol lowering properties of fenugreek; the majority of these studies have confirmed these effects. Apart from the physical effects of fibrous, mucilaginous compounds, and the saponins present in this product, which retard and limit the absorption of carbohydrates and cholesterol, some other compounds in this medicinal supplement have been introduced as the main cause of these effects: the amino acid 4-hydroxy isoleucine, which is the main amino acid present in this product, is mentioned among the main compounds responsible for lowering blood sugar, which exerts its effect through the possible mechanism of stimulating insulin excretion from pancreas. Furthermore, trigonelline and nicotinic acid have been introduced as antidiabetic agents. 

 
•    Before you use PHYTOPHAGE
Use during Pregnancy and Lactation
Due to its stimulating effects on the uterus, this product should NOT be used during pregnancy; to be used during lactation only with utmost care.
 

•    Taking PHYTOPHAGE
‎How and when to ‎take it 
Three times a day, take 2 tablets before meal.
‎ How long to take it 
In case of any physician recommendation, continue taking it until the visible symptoms have improved.
 
‎What to do if you miss a dose 
If you miss a dose of this product, try to take it as soon as remember if it’s almost time for the next dose, skip the missed dose and take your next dose at the regular time. Do not take two doses of it at the same time.
 

•    While you are taking PHYTOPHAGE
‎Things you must do‎ 

• Due to the presence of mucilaginous compounds in this product, other medications should be taken after an appropriate time interval.
• This medicinal supplement prevents iron absorption; therefore, it is recommended to take iron supplements at least two hours after taking this product.

‎Things you ‎must not do ‎ 

• Due to stimulating effects on the uterus, not to be taken by pregnant women.

‎Things to be careful of‎ 

• In patients using blood glucose lowering drugs, this drug should be used with caution and the blood sugar level has to be constantly monitored by the physician.
• In patients prone to drop in potassium levels, patients taking cardiac glycosides, or those with underlying cardiac conditions, this drug has to be used with care, as it lowers potassium levels.
• In individuals with allergy to legume family (Fabaceae), this product has to be taken with care, as there is a possibility of cross reaction.  
• In patients taking anticoagulant agents, it as to be taken with care, as it increases chances of hemorrhage.
• In children: due to a possibility of drop in blood sugar, it has to be taken with care.
• In case of concurrent use with other blood glucose lowering drugs, the patient should be monitored for hypoglycemia.
• The concurrent use of this product with mono Amine oxidase enzyme inhibitors (MAOIs) like tranylcypromide and isocarboxazid, hormonal drugs and anticoagulant drugs such as heparin and warfarin, and antiplatelet drugs and nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen, naproxen, cloprofen and indomethacin should be done with caution and as prescribed by a physician.

 
•    Side effects 
Dyspepsia, diarrhea, and generation of stomach and intestinal gas (flatulent) are the side effects of this product and allergic reactions (such as urticaria, itching, swelling in the lips and tongue, breathing problems) may occur with this medicinal suplementation. Furthermore, this drug can change the color and smell of urine. Also, the presence of coumarinic compounds and trypsin and chymotrypsin inhibitors in this drug can be hazardous.
 

•    After taking it
‎Storage 

• Keep the product in the package in a dry place, away from direct light, and below 25 °C.
• Keep out of sight and reach of children.

‎Disposal 
Do not put into sewer lines. Dispose in the everyday rubbish bin.‎
 

•    The Product ‎ 
‎What PHYTOPHAGE looks like 
Dosage Form: Tablet
Packaging: 3 blisters, each containing 10 tablets in cardboard box; patient information leaflet inside. 
 
‎Manufacturer 
This product is made from high quality local and imported herbs organically planted and ‎harvested. It has been formulated by ‎Iran Darouk Pharmaceuticals.‎